Course Schedule
Tuesday, March 25, 2025
|
7:15 - 8:00 am |
Registration & badge pickup |
All participants |
Vanderhoef
Theatre Lobby |
|
7:15 – 8:00 am |
Breakfast |
All participants |
Vanderhoef
Theatre Lobby |
|
8:00 – 8:50 am |
Session 1:
Overview - Neurotherapeutics Discovery and Development Process |
Michael A. Rogawski, M.D., Ph.D.,
University of California, Davis |
Vanderhoef Theatre, Mondavi Center |
|
8:50 - 9:40 am |
Session 2: Moving
from Hit to Lead to Clinical Candidate |
James Barrow, Ph.D., Johns Hopkins
School of Medicine |
Vanderhoef Theatre, Mondavi Center |
|
9:40
- 10:00 am |
BREAK |
||
|
10:00
- 10:50 am |
Session 3: ADME |
Kennan
Marsh, Ph.D., AbbVie |
Vanderhoef Theatre, Mondavi Center |
|
10:50 - 11:40 am |
Session 4: Toxicology |
Ruokun Wang, Ph.D., DABT, Biogen
|
Vanderhoef Theatre, Mondavi Center |
|
Intro to Mentors/Engagement Exercises |
Course Directors |
Vanderhoef Theatre, Mondavi Center |
|
|
11:45 am - 1:00 pm Rotation
1 |
LUNCH + Engagement Exercise 1: Meet Your Mentors |
Mentor Teams |
Mondavi
Center (2nd floor) |
|
1:00
- 1:50 pm |
Session 5: Animal Models |
Greg
Carr, Ph.D., Johns Hopkins School of Medicine |
Vanderhoef Theatre, Mondavi Center |
|
1:50
- 2:40 pm |
Session 6: Formulation
and Routes of Administration |
Maureen
Donovan, Ph.D., University of Iowa |
Vanderhoef Theatre, Mondavi Center |
|
2:40
- 3:00 pm |
BREAK |
||
|
3:00
- 3:50 pm |
Session 7: Alternative Routes of
Administration |
James
Cloyd, III, Pharm.D., University of Minnesota |
Vanderhoef Theatre, Mondavi Center |
|
3:50 - 4:10 pm |
Transition & Intro to Round Robins |
|
Vanderhoef
Theatre, Mondavi Center |
|
4:10
- 5:15 pm Rotat 3: 4:45 - 5:15 |
Engagement
Exercise 2: Round Robins 1 |
Mentor
Teams
|
Mondavi
Center (2nd floor) |
|
BREAK |
|||
|
6:00 - 8:00 pm |
Dinner &
Guest Lecture |
Tim Miller, M.D., Ph.D., Washington
University in St. Louis |
Vanderhoef Theatre, Mondavi Center |
Wednesday, March
26, 2025
|
7:15 – 8:00 am |
Breakfast |
|
Vanderhoef
Theatre Lobby |
|
8:00
- 8:05 am |
Daily intro -
Course Directors |
Barbara
Slusher |
Vanderhoef Theatre, Mondavi Center |
|
8:05
– 9:15 am |
Session 8: Adeno-associated virus (AAV) vectors & siRNA |
Dinah
Sah, Ph.D., Voyager Therapeutics |
Vanderhoef Theatre, Mondavi Center |
|
9:15
– 10:05 am |
Session 9: Antisense
Oligonucleotides |
Gene
Liau, Ph.D., Adagen Preclinical Solutions LLC and Tacit
Therapeutics |
Vanderhoef Theatre, Mondavi Center |
|
10:05 – 10:25 am |
BREAK |
||
|
10:25
– 11:15 am |
Session 10: Antibody
Therapies |
Gai
Ayalon, Ph.D., FOXG1 Research Foundation |
Vanderhoef Theatre, Mondavi Center |
|
11:15
am – 12:05 pm |
Session 11: Rigor in
Translational Drug Discovery and Development |
Shai
Silberberg, Ph.D., NINDS
|
Vanderhoef
Theatre, Mondavi Center |
|
LUNCH + Responsible
Conduct of Research Exercise #1 |
Mentor
Teams
|
Mondavi
Center (2nd floor) |
|
|
Session 12: Academic Drug
Discovery Vignettes |
Barbara
Slusher, Ph.D., MAS, Johns Hopkins Drug Discovery
|
Vanderhoef Theatre, Mondavi Center |
|
|
Session 13: Clinical
Considerations in the Non-Clinical Phase of Drug Discovery and Development |
James J. Vornov,
M.D., Ph.D., Johns Hopkins School of Medicine and Medpace
|
Vanderhoef Theatre, Mondavi Center |
|
|
3:30
– 3:45 pm |
BREAK |
||
|
3:45 - 3:55 pm |
Transition to Round Robins |
|
|
|
3:55 - 5:00 pm Rotat 4: 3:55 - 4:25 Rotat 5: 4:30 - 5:00 |
Engagement Exercise 3: Round Robin 2 |
Mentor
Teams |
Mondavi
Center (2nd floor) |
|
5:00
- 6:00 pm |
BREAK |
||
|
6:00
– 8:00 pm |
Dinner |
All
attendees |
AGR
Room, Walter A. Buehler Alumni Center |
Thursday, March
27, 2025
|
7:15 – 8:00 am |
Breakfast |
|
Vanderhoef
Theatre Lobby |
|
8:00
- 8:05 am |
Daily intro -
Course Directors |
Michael
Rogawski |
Vanderhoef Theatre, Mondavi Center |
|
8:05 – 8:55 am |
Session 15: Intellectual
Property |
Jeffrey
Childers, J.D., Ph.D., Casimir Jones |
Vanderhoef Theatre, Mondavi Center |
|
|
Session 16: Industry Partnerships and Newcos: What They Are and How to Make Them
Happen |
Matt
Tremblay, Ph.D., Blackbird Laboratories; Blackbird BioVentures
|
Vanderhoef Theatre, Mondavi Center |
|
BREAK |
|||
|
10:00 – 10:50 am |
Session 17: Funding
Academic Drug Discovery Research |
Charles
Cywin, Ph.D., NIH |
Vanderhoef Theatre, Mondavi Center |
|
10:50
- 11:00 am |
Transition to Round Robins |
||
|
11:00
am - 12:15 pm Rotat 6: 11:00 - 11:30 Rotat 7: 11:35 - 12:05 |
Engagement Exercise 4: Round Robin 3 |
Mentor Teams |
Mondavi
Center (2nd floor) |
|
12:15
- 1:15 pm |
LUNCH
- Responsible Conduct of Research case #2 |
|
Mondavi
Center (2nd floor) |
|
1:15
- 2:05 pm |
Session 18:
Target Validation |
James
Inglese, Ph.D., NCATS |
Vanderhoef Theatre, Mondavi Center |
|
2:30
- 4:00 pm |
Arboretum Walk - Guided Tour 2
groups - Rachel & Abbey (guides) |
All participants invited |
Meet
at Vanderhoef Theatre Lobby, then tour Arboretum |
|
4:00
– 6:00 pm |
Office Hours/Project work |
Faculty available - contact information
in program |
|
|
6:00 – 8:00 pm |
Dinner |
All participants |
AGR
Room, Walter A. Buehler Alumni Center |
Friday, March 28,
2025
|
7:15 – 8:00 am |
Breakfast |
|
King
Hall/Law School |
|
8:00 - 8:10 am |
Intro to Presentations |
Course
Directors |
King
Hall/Law School |
|
8:10 - 8:20 am |
Transition to Presentations |
|
|
|
8:20 – 11:30 am |
Engagement Exercise 5:
Student Presentations |
Mentor
Teams |
King
Hall/Law School |
|
11:30
am - 12:00 pm |
Conclusion: Where do we go
from here? Course evaluation; survey |
Course
Directors |
King
Hall/Law School |
|
12:00
pm |
Adjourn – Lunch
Grab & Go |
||
