Neurotherapeutics Course
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Training in Neurotherapeutics Discovery and Development

Training in Neurotherapeutics Discovery and Development
for Academic Scientists – 2023 Offering

March 14 - 17, 2023

Schedule

Tuesday, March 14, 2023

7:15 am – 8:00 am

Continental Breakfast

 

 

Hyatt Place UC Davis, Meeting Room

7:30 am – 8:00 am

Registration

 

Hyatt Place UC Davis, Meeting Room

8:00 am – 8:20 am

Overview: The Neurotherapeutics Discovery and Development Process

Michael A. Rogawski, M.D., Ph.D., University of California, Davis

Vanderhoef Theatre, Mondavi Center

8:20 am – 9:10 am

Session 1: Target and Pathway Interrogation

James Inglese, Ph.D., National Center for Advancing Translational Sciences, NIH

Vanderhoef Theatre, Mondavi Center

9:10 am – 10:00 am

 

Session 2: Moving from Hit to Lead to Clinical Candidate

James Barrow, Ph.D., Johns Hopkins School of Medicine

Vanderhoef Theatre, Mondavi Center

10:00 am  – 10:20 am

BREAK

 

Vanderhoef Theatre Lobby

10:20 am – 11:10 am

 

Session 3: ADME

Kennan Marsh, Ph.D., AbbVie

Vanderhoef Theatre, Mondavi Center

11:10 am – 12:00 pm 

 

Session 4: Antibody-Based Therapies

Gai Ayalon, Ph.D., Neumora Therapeutics

Vanderhoef Theatre, Mondavi Center

12:00 pm – 12:50 pm

LUNCH -  Engagement Exercise 1: Meet Your Mentors

Faculty & Participants

Mondavi Center

12:50 pm – 1:40 pm

 

Session 5: Adeno-associated viral vectors (AAVs)

Edgar Rodriguez-Lebron, Ph.D.,  Lacerta Therapeutics

Vanderhoef Theatre, Mondavi Center

1:40 pm – 2:30 pm

 

Session 6: Antisense Oligonucleotides (ASOs)

Gene Liau, Ph.D.

Vanderhoef Theatre, Mondavi Center

2:30 pm – 2:50 pm

BREAK

 

Vanderhoef Theatre Lobby

2:50 pm – 3:40 pm

Session 7: Animal Models

Greg Carr, Ph.D., Johns Hopkins

Vanderhoef Theater, Mondavi Center

3:40 – 3:45 pm

Intro to Round Robins

 

Vanderhoef Theatre

3:45 pm – 4:45 pm

Engagement Exercise 2: ROUND ROBIN 1

Mentor Teams

Mondavi Center

4:45 pm - 6:00 pm

BREAK

 

 

6:00 pm – 8:00 pm

Dinner

 

AGR Room, Walter A. Buehler Alumni Center

 

Wednesday, March 15, 2023

7:15 am – 8:00 am

 

Continental Breakfast

 

 

Hyatt Place

8:00 am – 8:50 am

Session 8: Formulation and Routes of Administration

Maureen Donovan, Ph.D., University of Iowa

Vanderhoef Theatre, Mondavi Center

8:50 am – 9:40 am

 

Session 9: Alternative Routes of Administration

James Cloyd, III, Pharm.D., University of Minnesota

Vanderhoef Theatre, Mondavi Center

9:40 am – 10:00 am

BREAK

 

Vanderhoef Theatre Lobby

10:00 am – 10:50 am

Session 10: Toxicology

Adaline Smith, Ph.D., DABT

Vanderhoef Theatre, Mondavi Center

10:50 am – 11:40 am

Session 11: IND Enabling Studies and Preparation of the IND

Ted Spack, Ph.D., AxoSim, Inc.

Vanderhoef Theatre, Mondavi Center

11:40 am – 1:50 pm

LUNCH
Responsible Conduct of Research Exercise

Faculty & Participants

Vanderhoef Theatre Lobby for lunch; can sit outside or in breakout rounds for exercise

1:50 pm – 2:40 pm

Session 12: Academic Drug Discovery Vignette

 

Barbara Slusher, Ph.D., MAS, Johns Hopkins Drug Discovery

Vanderhoef Theatre, Mondavi Center

2:40 pm – 3:30 pm

Session 13: Rigor in Translational Drug Discovery and Development

Shai Silberberg, Ph.D., NIH/NINDS

Vanderhoef Theatre, Mondavi Center

3:30 pm – 3:50 pm

BREAK

 

Vanderhoef Theatre Lobby

3:50 pm – 4:50 pm 

Engagement Exercise 3: Round Robin Day 2 (1 hr)

Mentor Teams

Mondavi Center breakouts

6:00 pm – 8:00 pm

 

Dinner and Guest Lecture

Adrian R. Krainer, Ph.D., Cold Spring Harbor Laboratory

Grand Tier Lobby, Mondavi Center

 

Thursday, March 16, 2023

7:15 am – 8:00 am

Continental Breakfast

 

 

Hyatt Place UC Davis

8:00 am – 8:50 am

Session 14: Intellectual Property

Jeffrey Childers, J.D., Ph.D., Casimir Jones

Vanderhoef Theatre, Mondavi Center

8:50 am – 9:40 am

Session 15: Clinical Considerations in the Non-Clinical Phase of Drug Discovery and Development

James J. Vornov, M.D., Ph.D., Johns Hopkins School of Medicine and Medpace

Vanderhoef Theatre, Mondavi Center

9:40 am – 10:00 am

BREAK

 

Vanderhoef Theatre Lobby

10:00 am – 10:50 am

Session 16: Funding Academic Drug Discovery Research

 

Charles L. Cywin, Ph.D., NIH/NINDS

Vanderhoef Theatre, Mondavi Center

11:00 am – 12:30 pm

Engagement Exercise 4: Round Robin Day 3 (1.5 hrs)

Barbara Slusher, Ph.D., Johns Hopkins University

Vanderhoef Theatre, Mondavi Center

12:30 pm – 1:30pm

LUNCH

 

Vanderhoef Theatre Lobby

2:00 pm – 3:30 pm

Arboretum Walk - Guided Tour (weather permitting)

All

Snacks before at Vanderhoef Theatre Lobby, then walk in Arboretum

3:30 pm – 6:00 pm

Office Hours/Project work

Faculty available  – contact info in program

 

6:00 pm – 8:30 pm

Dinner

Faculty & Participants

Conference Center Ballroom

 

Friday, March 17, 2023

7:15 am  –8:00 am

Continental Breakfast

 

 

 

8:00 am – 8:15 am

Intro to Presentations

Course Directors

Vanderhoef Theatre, Mondavi Center

8:15 am – 11:30 am

Engagement Exercise 4: Student Presentations

Faculty & Participants

King Hall - Rooms 1320, 2050, 2320, 2360

11:30 am –12:00 pm

Lunch/Conclusion Where do we go from here? Course evaluation; survey

Faculty & Participants

Vanderhoef Theatre, Mondavi Center

12:00 pm

Adjourn – Lunch

 

Mondavi Center

 

Collaborator’s Logos