TUESDAY, MARCH 25, 2025
|
8:00 — 8:30 am |
Continental Breakfast |
All participants |
Vanderhoef Theatre Lobby, Mondavi Center |
||
|
8:00 — 8:30 am |
Registration & badge pickup |
All participants |
Vanderhoef Theatre Lobby, Mondavi Center |
||
|
8:30 —9:20 am |
Session 1: Overview: The Neurotherapeutics Discovery and Development Process |
Michael A. Rogawski, M.D., Ph.D., University of California, Davis |
Vanderhoef Theatre, Mondavi Center |
||
|
9:20 — 10:10 am |
Session 2: Moving From Hit to Lead to Clinical Candidate |
James Barrow, Ph.D., Johns Hopkins School of Medicine |
Vanderhoef Theatre, Mondavi Center |
||
|
10:10 — 10:30 am |
BREAK |
||||
|
10:30 — 11:20 am |
Session 3: ADME |
Kennan Marsh, Ph.D., AbbVie |
Vanderhoef Theatre, Mondavi Center |
||
|
11:20 am — 12:10 pm |
Session 4: Toxicology |
Ruokun Wang, Ph.D., DABT |
Vanderhoef Theatre, Mondavi Center |
||
|
12:10 — 12:15 pm |
Introduction to Engagement Exercises |
Course Directors |
Vanderhoef Theatre, Mondavi Center |
||
|
12:15 — 1:40 pm |
Lunch & Engagement Exercise 1: Mentor Teams Meeting For team assignments: see Mentor Teams handout or course website |
Mentor Teams |
Mondavi Center, 3rd fl. |
||
|
1:40 — 2:30 pm |
Session 5: Animal Models |
Gregory Carr, Ph.D., Johns Hopkins School of Medicine |
Vanderhoef Theatre, Mondavi Center |
||
|
2:30 — 3:20 pm |
Session 6: Formulation and Routes of Administration |
Maureen Donovan, Ph.D., University of Iowa |
Vanderhoef Theatre, Mondavi Center |
||
|
3:20 — 3:25 pm |
Introduction to Round Robins |
Course Directors |
Vanderhoef Theatre, Mondavi Center |
||
|
3:25 — 3:50 pm |
Break/Transition to Round Robins |
||||
|
3:50 — 5:00 pm |
Engagement Exercise 2: Round Robins See Round Robins schedule handout on website |
Mentor Teams |
Mondavi Center, 3rd fl. |
||
|
3:50 — 4:20 pm |
Rotation 2 |
||||
|
4:30 — 5:00 pm |
Rotation 3 |
||||
|
5:00 — 6:00 pm |
BREAK |
||||
|
6:00 — 8:00 pm |
Dinner and Invited Guest Lecture |
All invited |
Mondavi Center, Vanderhoef Theatre |
||
|
|
Guest Lecture: RNA—Targeted Therapies for Neurodegenerative Disease |
Timothy Miller, M.D., Ph.D., Washington University in St. Louis |
Mondavi Center |
||
WEDNESDAY, MARCH 26, 2025
|
8:00 — 8:30 am |
Continental Breakfast |
All participants |
Vanderhoef Theatre Lobby, Mondavi Center |
|
8:30 — 8:35 am |
Welcome & Daily Overview |
Course Directors |
Vanderhoef Theatre, Mondavi Center |
|
8:35 — 9:25 am |
Session 7: Alternative Routes of Administration |
James Cloyd, Pharm.D., University of Minnesota |
Vanderhoef Theatre, Mondavi Center |
|
9:25— 10:30 am |
Session 8: Adeno—associated virus (AAV) Gene Therapies and Small Interfering RNA (siRNA) Therapeutics |
Dinah Sah, Ph.D. |
Vanderhoef Theatre, Mondavi Center |
|
10:30 — 10:50 am |
BREAK |
||
|
10:50 — 11:40 am |
Session 9: Antisense Oligonucleotides |
Gene Liau, Ph.D., Adagen Preclinical Solutions and Tacit Therapeutics |
Vanderhoef Theatre, Mondavi Center |
|
11:40 am —12:30 pm |
Session 10: Antibody Therapies |
Gai Ayalon, Ph.D., FOXG1 Research Foundation |
Vanderhoef Theatre, Mondavi Center |
|
12:30 — 2:00 pm |
Lunch & Responsible Conduct of Research Exercise 1 |
Mentor Teams |
Mondavi Center, 3rd fl. |
|
2:00 — 2:50 pm |
Session 11: Rigor in Translational Drug Discovery and Development |
Shai Silberberg, Ph.D., National Institute of Neurological Disorders and Stroke (NINDS) |
Vanderhoef Theatre, Mondavi Center |
|
2:50 — 3:15 pm |
Break/Transition to Round Robins |
|
|
|
3:15 — 4:25 pm |
Engagement Exercise 3: Round Robins |
Mentor Tearns |
Mondavi Center, 3rd fl. |
|
3:15 — 3:45 pm |
Rotation 4 |
||
|
3:55 — 4:25 pm |
Rotation 5 |
||
|
4:30 — 6:00 pm |
BREAK |
||
|
6:00 — 8:00 pm |
Dinner |
All invited |
AGR Room, Walter A. Buehler Alumni Center |
THURSDAY, MARCH 27, 2025
|
8:00 — 8:30 am |
Continental Breakfast |
All participants |
Vanderhoef Theatre Lobby, Mondavi Center |
|
8:30 — 8:35 am |
Welcome & Daily Overview |
Course Directors |
Vanderhoef Theatre, Mondavi Center |
|
8:35 — 9:25 am |
Session 12: Academic Drug Discovery Vignettes |
Barbara Slusher, Ph.D., MAS, Johns Hopkins School of Medicine |
Vanderhoef Theatre, Mondavi Center |
|
9:25 — 10:15 am |
Session 13: Clinical Considerations in the Non— Clinical Phase of Drug Discovery and Development |
James Vornov, M.D., Ph.D., Johns Hopkins School of Medicine and Medpace |
Vanderhoef Theatre, Mondavi Center |
|
10:15 — 10:35 am |
BREAK |
||
|
10:35 — 11:25 am |
Session 14: Intellectual Property |
Jeffrey Childers, J.D., Ph.D., Casimir Jones |
Vanderhoef Theatre, Mondavi Center |
|
11:25 am — 12:15 pm |
Session 15: Industry Partnerships and Newcos: What They Are and How to Make Them Happen |
Matt Tremblay, Ph.D., Blackbird Laboratories; Blackbird BioVentures |
Vanderhoef Theatre, Mondavi Center |
|
12:15 — 1:15 pm |
LUNCH & Responsible Conduct of Research Exercise 2 |
Mentor Teams |
Mondavi Center, 3rd fl. |
|
1:15 — 1:20 pm |
Transition to Round Robins |
||
|
1:20 — 2:30 pm |
Engagement Exercise 4: Round Robins |
Mentor Tearns |
Mondavi Center, 3rd fl. |
|
1:20 — 1:50 pm |
Rotation 6 |
||
|
2:00 — 2:30 pm |
Rotation 7 |
||
|
2:45 — 3:05 pm |
Meet & Walk to Arboretum |
All invited |
Meet outside Mondavi Center at 2:45 pm |
|
3:10 — 4:10 pm |
Guided Tour — Arboretum |
All invited |
UC Davis Arboretum |
|
4:30 — 6:00 pm |
BREAK |
||
|
6:00 — 8:00 pm |
Dinner |
All participants |
AGR Room, Walter A. Buehler Alumni Center |
FRIDAY, MARCH 28, 2025
All Friday activities
take place at King Hall, UC Davis Law School
|
7:30 — 8:00 am |
Continental Breakfast |
All participants |
Hallway outside Room 1001, King Hall |
|
8:00 — 8:15 am |
Introduction to Presentations |
Course Directors |
Room 1001, King Hall |
|
8:30 — 11:30 am |
Engagement Exercise 5:Student Presentations See Presentation Schedule handout or course website |
Mentor Teams |
Rooms 1320, 2040, 2320, 2360, King Hall |
|
11:30 am — 12:00 pm |
Conclusion: Where do we go from here? Course evaluation; survey |
Course Directors |
Room 1001, King Hall |
|
12:00 pm |
Course Adjourns & Lunch (pick up box lunch) |
|
Hallway outside Room 1001, King Hall |
