Training in Neurotherapeutics Discovery
and Development
for Academic Scientists – 2023 Offering
March 14 - 17, 2023
Schedule
Tuesday, March 14, 2023
|
7:15 am – 8:00 am |
Continental
Breakfast |
|
Hyatt Place
UC Davis, Meeting Room |
|
7:30 am – 8:00 am |
Registration |
|
Hyatt Place
UC Davis, Meeting Room |
|
8:00 am – 8:20 am |
Overview:
The Neurotherapeutics Discovery and Development Process |
Michael A. Rogawski, M.D., Ph.D., University of
California, Davis |
Vanderhoef Theatre, Mondavi Center |
|
8:20 am – 9:10 am |
Session
1: Target and Pathway Interrogation |
James
Inglese, Ph.D., National Center for Advancing Translational Sciences, NIH |
Vanderhoef Theatre, Mondavi Center |
|
9:10 am – 10:00 am |
Session
2: Moving from Hit to Lead to Clinical Candidate |
James Barrow, Ph.D., Johns Hopkins School of
Medicine |
Vanderhoef Theatre, Mondavi Center |
|
10:00 am –
10:20 am |
BREAK |
|
Vanderhoef Theatre Lobby |
|
10:20 am – 11:10 am |
Session
3: ADME |
Kennan Marsh,
Ph.D., AbbVie |
Vanderhoef Theatre, Mondavi Center |
|
11:10 am – 12:00 pm |
Session 4: Antibody-Based Therapies |
Gai Ayalon, Ph.D., Neumora Therapeutics |
Vanderhoef Theatre, Mondavi Center |
|
12:00 pm – 12:50 pm |
LUNCH
- Engagement Exercise 1: Meet Your
Mentors |
Faculty & Participants |
Mondavi
Center |
|
12:50 pm – 1:40 pm |
Session
5: Adeno-associated viral vectors (AAVs) |
Edgar
Rodriguez-Lebron, Ph.D., Lacerta
Therapeutics |
Vanderhoef Theatre, Mondavi Center |
|
1:40 pm – 2:30 pm |
Session 6: Antisense Oligonucleotides (ASOs) |
Gene Liau,
Ph.D. |
Vanderhoef Theatre, Mondavi Center |
|
2:30 pm – 2:50 pm |
BREAK |
|
Vanderhoef
Theatre Lobby
|
|
2:50 pm –
3:40 pm |
Session 7: Animal Models |
Greg
Carr, Ph.D., Johns Hopkins
|
Vanderhoef Theater, Mondavi Center |
|
Intro to Round Robins |
|
Vanderhoef Theatre |
|
|
3:45 pm – 4:45 pm |
Engagement Exercise 2: ROUND ROBIN 1 |
Mentor
Teams
|
Mondavi Center |
|
BREAK |
|
|
|
|
6:00 pm – 8:00 pm |
Dinner |
|
AGR Room, Walter A. Buehler Alumni Center |
Wednesday, March 15, 2023
|
7:15 am – 8:00 am |
Continental Breakfast |
|
Hyatt Place |
|
8:00 am – 8:50 am |
Session 8:
Formulation and Routes of Administration |
Maureen Donovan, Ph.D.,
University of Iowa |
Vanderhoef Theatre, Mondavi Center |
|
8:50 am – 9:40 am |
Session 9:
Alternative Routes of
Administration |
James Cloyd, III, Pharm.D.,
University of Minnesota |
Vanderhoef Theatre, Mondavi Center |
|
9:40 am – 10:00 am |
BREAK |
|
Vanderhoef
Theatre Lobby |
|
10:00 am – 10:50 am |
Session 10: Toxicology |
Adaline Smith, Ph.D., DABT |
Vanderhoef Theatre, Mondavi Center |
|
10:50 am – 11:40 am |
Session 11:
IND Enabling Studies and
Preparation of the IND |
Ted Spack,
Ph.D., AxoSim, Inc. |
Vanderhoef Theatre, Mondavi Center |
|
LUNCH |
Faculty & Participants |
Vanderhoef Theatre
Lobby for lunch; can sit outside or in breakout rounds for exercise |
|
|
1:50 pm – 2:40 pm |
Session 12: Academic
Drug Discovery Vignette |
Barbara Slusher, Ph.D.,
MAS, Johns Hopkins Drug Discovery |
Vanderhoef Theatre, Mondavi Center |
|
2:40 pm – 3:30 pm |
Session 13: Rigor
in Translational Drug Discovery and Development |
Shai
Silberberg, Ph.D., NIH/NINDS
|
Vanderhoef Theatre, Mondavi Center |
|
BREAK |
|
Vanderhoef Theatre Lobby |
|
|
3:50 pm – 4:50 pm
|
Engagement Exercise
3: Round Robin Day 2 (1 hr) |
Mentor Teams |
Mondavi Center breakouts |
|
6:00 pm –
8:00 pm |
Dinner and Guest Lecture |
Adrian R.
Krainer, Ph.D., Cold Spring Harbor Laboratory |
Grand Tier
Lobby, Mondavi Center |
Thursday, March 16, 2023
|
7:15 am – 8:00 am |
Continental Breakfast |
|
Hyatt Place
UC Davis |
|
8:00 am – 8:50 am |
Session 14: Intellectual Property |
Jeffrey
Childers, J.D., Ph.D., Casimir Jones |
Vanderhoef Theatre, Mondavi Center |
|
Session
15: Clinical Considerations in the Non-Clinical Phase of
Drug Discovery and Development |
James J. Vornov, M.D., Ph.D., Johns Hopkins School
of Medicine and Medpace |
Vanderhoef Theatre, Mondavi Center |
|
|
9:40 am – 10:00 am |
BREAK |
|
Vanderhoef Theatre Lobby |
|
10:00 am – 10:50 am |
Session 16: Funding Academic Drug Discovery
Research |
Charles L.
Cywin, Ph.D., NIH/NINDS |
Vanderhoef Theatre, Mondavi Center |
|
11:00 am –
12:30 pm |
Engagement
Exercise 4: Round Robin Day 3 (1.5 hrs) |
Barbara Slusher, Ph.D., Johns Hopkins
University
|
Vanderhoef Theatre, Mondavi Center |
|
LUNCH |
|
Vanderhoef Theatre Lobby |
|
|
2:00 pm – 3:30 pm |
Arboretum
Walk - Guided Tour (weather permitting) |
All |
Snacks before
at Vanderhoef Theatre Lobby, then walk in Arboretum |
|
3:30 pm –
6:00 pm |
Office Hours/Project work |
Faculty available – contact info in program |
|
|
6:00 pm – 8:30 pm |
Dinner |
Faculty &
Participants |
Conference
Center Ballroom |
Friday, March 17, 2023
|
7:15 am –8:00
am |
Continental Breakfast |
|
|
|
8:00 am – 8:15 am |
Intro
to Presentations |
Course
Directors |
Vanderhoef Theatre, Mondavi Center |
|
8:15 am – 11:30 am |
Engagement
Exercise 4: Student Presentations |
Faculty &
Participants |
King Hall -
Rooms 1320, 2050, 2320, 2360 |
|
11:30 am –12:00 pm |
Lunch/Conclusion
Where do we go from here? Course evaluation; survey |
Faculty &
Participants |
Vanderhoef Theatre, Mondavi Center |
|
12:00 pm |
Adjourn –
Lunch |
|
Mondavi Center |
