Neurotherapeutics Course
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2025 Neurotherapeutics Course Schedule

TUESDAY, MARCH 25, 2025

8:00 — 8:30 am

Continental Breakfast

All participants

Vanderhoef Theatre Lobby, Mondavi Center

8:00 — 8:30 am

Registration & badge pickup

All participants

Vanderhoef Theatre Lobby, Mondavi Center

8:30 —9:20 am

Session 1: Overview: The Neurotherapeutics Discovery and Development Process

Michael A. Rogawski, M.D., Ph.D., University of California, Davis

Vanderhoef Theatre, Mondavi Center

9:20 — 10:10 am

Session 2: Moving From Hit to Lead to Clinical Candidate

James Barrow, Ph.D., Johns Hopkins School of Medicine

Vanderhoef Theatre, Mondavi Center

10:10 — 10:30 am

BREAK

10:30 — 11:20 am

Session 3: ADME

Kennan Marsh, Ph.D., AbbVie

Vanderhoef Theatre, Mondavi Center

11:20 am — 12:10 pm

Session 4: Toxicology

Ruokun Wang, Ph.D., DABT

Vanderhoef Theatre, Mondavi Center

12:10 — 12:15 pm

Introduction to Engagement Exercises

Course Directors

Vanderhoef Theatre, Mondavi Center

12:15 — 1:40 pm

Lunch & Engagement Exercise 1: Mentor Teams Meeting

For team assignments: see Mentor Teams handout or course website

Mentor Teams

Mondavi Center, 3rd fl.

1:40 — 2:30 pm

Session 5: Animal Models

Gregory Carr, Ph.D., Johns Hopkins School of Medicine

Vanderhoef Theatre, Mondavi Center

2:30 — 3:20 pm

Session 6: Formulation and Routes of Administration

Maureen Donovan, Ph.D., University of Iowa

Vanderhoef Theatre, Mondavi Center

3:20 — 3:25 pm

Introduction to Round Robins

Course Directors

Vanderhoef Theatre, Mondavi Center

3:25 — 3:50 pm

Break/Transition to Round Robins

3:50 — 5:00 pm

Engagement Exercise 2: Round Robins

See Round Robins schedule handout on website

Mentor Teams

Mondavi Center, 3rd fl.

3:50 — 4:20 pm

Rotation 2

4:30 — 5:00 pm

Rotation 3

5:00 — 6:00 pm

BREAK

6:00 — 8:00 pm

Dinner and Invited Guest Lecture

All invited

Mondavi Center, Vanderhoef Theatre

 

Guest Lecture: RNA—Targeted Therapies for Neurodegenerative Disease

Timothy Miller, M.D., Ph.D., Washington University in St. Louis

Mondavi Center

WEDNESDAY, MARCH 26, 2025

8:00 — 8:30 am

Continental Breakfast

All participants

Vanderhoef Theatre Lobby, Mondavi Center

8:30 — 8:35 am

Welcome & Daily Overview

Course Directors

Vanderhoef Theatre, Mondavi Center

8:35 — 9:25 am

Session 7: Alternative Routes of Administration

James Cloyd, Pharm.D., University of Minnesota

Vanderhoef Theatre, Mondavi Center

9:25— 10:30 am

Session 8: Adeno—associated virus (AAV) Gene Therapies and Small Interfering RNA (siRNA) Therapeutics

Dinah Sah, Ph.D.

Vanderhoef Theatre, Mondavi Center

10:30 — 10:50 am

BREAK

10:50 — 11:40 am

Session 9: Antisense Oligonucleotides

Gene Liau, Ph.D., Adagen Preclinical Solutions and Tacit Therapeutics

Vanderhoef Theatre, Mondavi Center

11:40 am —12:30 pm

Session 10: Antibody Therapies

Gai Ayalon, Ph.D., FOXG1 Research Foundation

Vanderhoef Theatre, Mondavi Center

12:30 — 2:00 pm

Lunch & Responsible Conduct of Research Exercise 1

Mentor Teams

Mondavi Center, 3rd fl.

2:00 — 2:50 pm

Session 11: Rigor in Translational Drug Discovery and Development

Shai Silberberg, Ph.D., National Institute of Neurological Disorders and Stroke (NINDS)

Vanderhoef Theatre, Mondavi Center

2:50 — 3:15 pm

Break/Transition to Round Robins

 

3:15 — 4:25 pm

Engagement Exercise 3: Round Robins

Mentor Tearns

Mondavi Center, 3rd fl.

3:15 — 3:45 pm

Rotation 4

3:55 — 4:25 pm

Rotation 5

4:30 — 6:00 pm

BREAK

6:00 — 8:00 pm

Dinner

All invited

AGR Room, Walter A. Buehler Alumni Center

THURSDAY, MARCH 27, 2025

8:00 — 8:30 am

Continental Breakfast

All participants

Vanderhoef Theatre Lobby, Mondavi Center

8:30 — 8:35 am

Welcome & Daily Overview

Course Directors

Vanderhoef Theatre, Mondavi Center

8:35 — 9:25 am

Session 12: Academic Drug Discovery Vignettes

Barbara Slusher, Ph.D., MAS, Johns Hopkins School of Medicine

Vanderhoef Theatre, Mondavi Center

9:25 — 10:15 am

Session 13: Clinical Considerations in the Non— Clinical Phase of Drug Discovery and Development

James Vornov, M.D.,

Ph.D., Johns Hopkins School of Medicine and Medpace

Vanderhoef Theatre, Mondavi Center

10:15 — 10:35 am

BREAK

10:35 — 11:25 am

Session 14: Intellectual Property

Jeffrey Childers, J.D., Ph.D., Casimir Jones

Vanderhoef Theatre, Mondavi Center

11:25 am — 12:15 pm

Session 15: Industry Partnerships and Newcos: What They Are and How to Make Them Happen

Matt Tremblay, Ph.D., Blackbird Laboratories; Blackbird BioVentures

Vanderhoef Theatre, Mondavi Center

12:15 — 1:15 pm

LUNCH & Responsible Conduct of Research Exercise 2

Mentor Teams

Mondavi Center, 3rd fl.

1:15 — 1:20 pm

Transition to Round Robins

1:20 — 2:30 pm

Engagement Exercise 4: Round Robins

Mentor Tearns

Mondavi Center, 3rd fl.

1:20 — 1:50 pm

Rotation 6

2:00 — 2:30 pm

Rotation 7

2:45 — 3:05 pm

Meet & Walk to Arboretum

All invited

Meet outside Mondavi Center at 2:45 pm

3:10 — 4:10 pm

Guided Tour — Arboretum

All invited

UC Davis Arboretum

4:30 — 6:00 pm

BREAK

6:00 — 8:00 pm

Dinner

All participants

AGR Room, Walter A. Buehler Alumni Center

FRIDAY, MARCH 28, 2025

All Friday activities take place at King Hall, UC Davis Law School

7:30 — 8:00 am

Continental Breakfast

All participants

Hallway outside Room 1001, King Hall

8:00 — 8:15 am

Introduction to Presentations

Course Directors

Room 1001, King Hall

8:30 — 11:30 am

Engagement Exercise 5:Student Presentations

 

See Presentation Schedule handout or course website

Mentor Teams

Rooms 1320, 2040, 2320, 2360, King Hall

11:30 am — 12:00 pm

Conclusion: Where do we go from here? Course evaluation; survey

Course Directors

Room 1001, King Hall

12:00 pm

Course Adjourns & Lunch (pick up box lunch)

 

Hallway outside Room 1001, King Hall

 

Collaborator’s Logos