Neurotherapeutics Course
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Course Schedule

Tuesday, March 12, 2024

7:00  – 8:00 am

Registration & badge pickup

All participants

Regency Ballroom Foyer

8:00 – 8:50 am

Session 1: Overview  – Neurotherapeutics Discovery and Development Process

Michael A. Rogawski, M.D., Ph.D., University of California, Davis

Cabinet / Judiciary

8:50  – 9:40 am

Session 2: Moving from Hit to Lead to Clinical Candidate

James Barrow, Ph.D., Johns Hopkins School of Medicine

Cabinet / Judiciary

9:40 – 10:00 am

BREAK

10:00  – 10:50 am

Session 3: ADME

Kennan Marsh, Ph.D., AbbVie

Cabinet / Judiciary

10:50  – 11:40 am

Session 4: Toxicology 

Ruokun Wang, Ph.D., DABT, Biogen

Cabinet / Judiciary

11:40  – 11:45 am

Intro to Mentors/Engagement Exercises

Course Directors

Cabinet / Judiciary

11:45 am  – 1:00 pm

LUNCH / Engagement Exercise 1: Meet Your Mentors

Mentor Teams

Severn; Potomac; Patuxent; Embassy

1:00  – 1:50 pm

Session 5: Animal Models

Greg Carr, Ph.D., Johns Hopkins School of Medicine

Cabinet / Judiciary

1:50  – 2:40 pm

Session 6: Formulation and Routes of Administration

Maureen Donovan, Ph.D., University of Iowa

Cabinet / Judiciary

2:40 – 3:00 pm

BREAK

3:00  – 3:50 pm

Session 7: Alternative Routes of Administration

James Cloyd, III, Pharm.D., University of Minnesota

Cabinet / Judiciary

3:50 – 4:10 pm

Transition & Introduction to Round Robins

 

Cabinet / Judiciary

4:10 – 5:15 pm

Engagement Exercise 2: Round Robins 1

Mentor Teams

Severn; Potomac; Patuxent; Embassy

5:15 – 6:00 pm

BREAK

6:00 – 8:00 pm

ASENT Career Dinner

All participants

Regency I

Wednesday, March 13, 2024

8:00 – 8:05 am

Daily Introduction

Course Directors 

Cabinet / Judiciary

8:05 – 8:55 am

Session 8: Adeno-associated virus (AAV) vectors

Steven Gray, Ph.D., UT Southwestern Medical Center

Cabinet / Judiciary

8:55 – 9:45 am

Session 9: Antisense Oligonucleotides

Gene Liau, Ph.D., Adagen Preclinical Solutions LLC and Tacit Therapeutics

Cabinet / Judiciary

9:45 – 10:00 am

BREAK

10:00 – 10:50 am

Session 10: Antibody Therapies

Gai Ayalon, Ph.D., FOXG1 Research Foundation

Cabinet / Judiciary

10:50 – 11:40 am

Session 11: Cellular Therapies

Arnold R. Kriegstein, M.D., Ph.D., UCSF School of Medicine

Cabinet / Judiciary

11:40 am – 1:00 pm

LUNCH / Responsible Conduct of Research Exercise #1

Mentor Teams

Severn; Potomac; Patuxent; Embassy

1:00 – 1:50 pm

Session 12: Rigor in Translational Drug Discovery and Development

Shai Silberberg, Ph.D., NINDS

Cabinet / Judiciary

1:50 – 2:40 pm

Session 13: Academic Drug Discovery Vignettes

Barbara Slusher, Ph.D., MAS, Johns Hopkins Drug Discovery

Cabinet / Judiciary

2:40 – 2:55 pm

BREAK

2:55 – 3:45 pm

Session 14: Clinical Considerations in the Non-Clinical Phase of Drug Discovery and Development

James J. Vornov, M.D., Ph.D., Johns Hopkins School of Medicine and Medpace

 

Cabinet / Judiciary

3:45 – 3:55 pm

Transition to Round Robins

 

 

3:55 – 5:00 pm

Engagement Exercise 3: Round Robins

Mentor Teams

Severn; Potomac; Patuxent; Embassy

5:00 – 6:00 pm

BREAK

6:00 – 8:00 pm

Dinner and Guest Lecture

Irfan Qureshi, M.D., Biohaven

Regency I

Thursday, March 14, 2024

8:00 – 8:05 am

Daily intro - Course Directors

Course Directors

Cabinet / Judiciary

8:05 – 8:55 am

Session 15: Intellectual Property

Jeffrey Childers, J.D., Ph.D., Casimir Jones

Cabinet / Judiciary

8:55 – 9:45 am

Session 16: Industry Partnerships and Newcos: What They Are and How to Make Them Happen

Matt Tremblay, Ph.D., Blackbird Laboratories

Cabinet / Judiciary

9:45 – 10:00 am

BREAK

10:00 – 10:50 am

Session 17: Funding Academic Drug Discovery Research

Charles Cywin, Ph.D., NINDS

Cabinet / Judiciary

10:50 – 11:00 am

Transition to Round Robins

11:00 am – 12:15 pm

Engagement Exercise 4: Round Robin

Mentor Teams

Severn; Potomac; Patuxent; Embassy

12:15 – 1:15 pm

LUNCH / Responsible Conduct of Research case #2

 

Severn; Potomac; Patuxent; Embassy

1:15 – 2:05 pm

Session 18: Target Validation and Introduction to NCATS Tour

James Inglese, Ph.D., NCATS

Cabinet / Judiciary

2:05 – 2:30 pm

Transition to NCATS Tour bus

2:30 – 3:00 pm

Bus trip to NCATS

3:00 – 4:30 pm

NCATS Tour

4:30 – 5:00 pm

Return trip to hotel

5:00 – 6:00 pm

BREAK

6:00 – 8:00 pm

Dinner

All

TBA

Friday, March 15, 2024

8:00 – 8:10 am

Intro to Presentations

Course Directors

Cabinet / Judiciary

8:10 – 8:20 am

Transition to Presentations

 

 

8:20 – 11:30 am

Engagement Exercise 5: Student Presentations

Mentor Teams

Severn; Potomac; Patuxent; Embassy

11:30 am – 12:00 pm

Conclusion: Where do we go from here?

Course Directors

Cabinet / Judiciary

12:00 pm

Adjourn – Grab & Go Lunch

 

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