Wednesday, February 19, 2014
|
7:45 am – 8:30 am |
Breakfast |
|
8:30 am – 9:00 am |
Overview: The Neurotherapeutics Discovery and Development Process Course Directors |
|
9:00 am – 10:00 am |
Lecture 1: Target and Pathway Interrogation Douglas Auld, PhD,
Novartis Institutes for Biomedical Research |
|
10:00 am – 10:10 am |
Break |
|
10:10 am – 11:10 am |
Lecture 2: Biology Basics for Identifying Hits William Janzen, BS,
University of North Carolina, Chapel Hill |
|
11:10 am – 12:10 pm |
Lecture 3: Moving from Hit to Lead to Clinical Candidate James Barrow, PhD,
Johns Hopkins School of Medicine |
|
12:10 pm – 1:30 pm |
Lunch (Students paired with mentors) |
|
1:30 pm – 2:30 pm |
Lecture 4: Medicinal Chemistry Craig Lindsley, PhD,
Vanderbilt University Medical Center |
|
2:30 pm – 3:30 pm |
Lecture 5: Alternative Approaches to Lead Generation Sam Enna, PhD,
University of Kansas |
|
3:30 pm – 3:45 pm |
Break |
|
3:45 pm – 5:30 pm |
Engagement Exercise
1: Clarify vision statement and begin to develop the components of mock
translations grant application |
|
5:30 pm – 6:15 pm |
Networking Reception |
|
6:15 pm – 7:00 pm |
Dinner |
|
7:00 pm – 8:15 pm |
After Dinner Talk: Drug Discovery Solomon Snyder, MD, DSc, DPhil, Johns Hopkins University |
Thursday, February 20, 2014
|
7:15 am – 8:00 am |
Breakfast |
|
8:00 am – 9:00 am |
Lecture 6: ADME Kennan Marsh, PhD,
AbbVie |
|
9:00 am – 10:00 am |
Lecture 7: Formulation and Route of Administration Heike Wulff, PhD,
University of California, Davis |
|
10:00 am – 10:10 am |
Break |
|
10:10 am – 11:10 am |
Lecture 8: Preclinical Proof-Concept / Target Engagement Studies Kalpana Merchant, PhD,
Eli Lilly and Company |
|
11:10 am – 12:10 pm |
Lecture 9: Toxicology Adaline Smith,
Ironwood Pharmaceuticals |
|
12:10 pm – 1:30 pm |
Lunch (Responsible conduct of research exercise) |
|
1:30 pm – 1:45 pm |
Break |
|
1:45 pm – 5:45 pm |
Engagement Exercise 2: Round-Robin – Students interact individually with each subject expert |
|
5:45 pm – 6:30 pm |
Networking Reception – ASENT Annual Meeting |
|
6:30 pm – 7:30 pm |
ASENT Annual Meeting Dinner |
|
7:30 pm – 9:00 pm |
Reserved for students to prepare mock translation grant applications; mentors available |
Friday, February 21, 2014
|
7:15 am – 8:00 am |
Breakfast |
|
8:00 am – 9:00 am |
Lecture 11: Experimental Medicine and Biomarkers Ajay Verma, MD, PhD,
Biogen Idec |
|
9:00 am – 10:00 am |
Lecture 10: IND Enabling Studies and Preparation of the IND William Bracken,
PhD, DABT, AbbVie |
|
10:00 am – 10:10 am |
Break |
|
10:10 am – 11:10 am |
Lecture 12: Interacting with the FDA Russell Katz, MD,
FDA Center for Drug Evaluation & Research |
|
11:10 am – 12:10 pm |
Lecture 13: Intellectual Property Kenneth A. Weber, PhD, JD, Partner, Kilpatrick Townsend & Stockton LLP |
|
12:10 pm – 2:00 pm |
Lunch |
|
2:15 pm – 6:00 pm |
Pipeline Session -ASENT 15th Annual Meeting Brief presentations on ongoing corporate and academic
neurotherapeutic R&D projects |
|
6:30 pm – 8:30 pm |
Restaurant Dinner |
Saturday, February 22, 2014
|
7:15 am – 8:00 am |
Breakfast |
|
8:00 am – 9:00 am |
Lecture 14: Funding Academic Drug Discovery Research Rebecca Farkas, PhD,
NIH/NINDS |
|
9:00 am – 10:15 am |
Engagement Exercise 3: Student Presentations – Description of mock translational grant application followed by critique |
|
10:15 am – 10:30 am |
Break |
|
10:30 am – 11:45 am |
Engagement Exercise 3: Continued |
|
11:45 am – 12:00 pm |
Lecture 15: Where Do We Go From Here? Presentation of Plan for Continued Mentoring, Engagement and Course Evaluation over Two-Year Period Course Directors |
|
12:00 pm |
Adjourn |